Dr. Nina Stourman

Associate Professor
Dr. Nina Stourman - profile photo

Dr. Nina Stourman

Associate Professor

Chemical & Biological Sciences

Ward Beecher Hall 6027

phone: (330) 941-7112

nvstourman@ysu.edu

Research Interests

Bacterial functional genomics, applications of enzymes

Teaching Interests

Biochemistry, Allied Health Chemistry, Chemical Toxicology

  • Education
    • 1992

      Ph D, Bioorganic Chemistry and Chemistry of Natural Bioactive Compounds

      Moscow State University (Russia)

    • 1984

      BS, Chemistry

      Moscow State University (Russia)

  • Awards and Honors
    • 2019

      YSU

      Distinguished Professor in Teaching Award

    • 2009

      Youngstown State University

      Research Professorship

  • Past History
    • 2014

      Youngstown State University

      Associate Professor

    • 2007

      Youngstown State University

      Assistant Professor

    • 2004

      Vanderbilt University

      Research Fellow

    • 2003

      Roswell Park Cancer Institute

      Affiliate Member

    • 1999

      Vanderbilt University

      Research Fellow

    • 1996

      University of Tennessee

      Research Trainee

    • 1992

      Hoffmann – La Roche, Inc

      Research Associate

  • Intellectual Contributions
    • 2023

      "Periplasmic β-glucosidase BglX from E. coli demonstrates greater activity towards galactose-containing substrates"

      International Journal of Biochemistry and Molecular Biology, volume 14, issue 4, p. 76-86

    • 2022

      "U.S. Academic Decathlon’s Science Student Exercise Book"

    • 2018

      "Analysis of lactase in lactose intolerance supplements."

      Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, volume 46, issue 6, p. 652-662

    • 2013

      "Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure"

      SciKnow Publications; Biochemistry and Molecular Biology, volume 1, issue 3, p. 52

    • 2012

      "Comparison of the functions of glutathionylspermidine synthetase/amidase from E. coli and its predicted homologues YgiC and YjfC."

      International journal of biochemistry and molecular biology, volume 3, issue 3, p. 302-12

    • 2011

      "Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia coli."

      Biochemistry, volume 50, issue 7, p. 1274-81

    • 2009

      "Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase."

      Biochemistry, volume 48, issue 28, p. 6559-61

    • 2007

      "Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET."

      Archives of biochemistry and biophysics, volume 464, issue 2, p. 221-7

    • 2005

      "Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta."

      Oncogene, volume 24, issue 32, p. 5043-52

    • 2005

      "Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins."

      Free radical biology & medicine, volume 38, issue 3, p. 375-87

    • 2003

      "Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11."

      Biochemistry, volume 42, issue 37, p. 11048-56

    • 2002

      "Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase."

      Biochemistry, volume 41, issue 51, p. 15161-72

    • 2001

      "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes."

      Chemical research in toxicology, volume 14, issue 8, p. 1107-17

    • 2001

      "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and dihalomethanes."

      Chemical research in toxicology, volume 14, issue 8, p. 1118-27

    • "Crystal Structure Analysis of yghU from E. Coli"

      Worldwide Protein Data Bank

  • Professional Service
    • Unknown

      Other
      American Chemical Society

    • Unknown

      Reviewer, Textbook
      Lehninger's Essential Interactions in Biochemistry 1e

    • Unknown

      Reviewer, Journal Article
      Biochemistry (ACS)

  • Public Service
    • Unknown

      Organizer
      Hands on Activities for STEAM class at Harding Elementary School
      Youngstown, Ohio

    • Unknown

      Organizer
      Jefferson High School Visit
      Jefferson, OH

    • 2015 - 2015

      Volunteer
      School visit
      Warren, Ohio

headshot


Education

B.S./M.S.: Moscow State University

Ph.D.: Moscow State University

Research Fellow: Vanderbilt University, Biochemistry, Nashville, TN, 1999-2003 & 2004-2007


Research Interests

Bacterial functional genomics during response to stress; bacterial glutathione metabolism


Publications

Nina Stourman, Jennifer Moore. Analysis of lactase in lactose intolerance supplements. Biochemistry and Molecular Biology Education, 46(6):652–662, 2018

Morse Z, Ballester A, Sui L, Stourman NV. Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure. Biochemistry & Molecular Biology (SciKnow Publications) (2013); 1(3): 52-57.

L Sui, JC Warren, JPN Russell, NV Stourman. Comparison of the functions of E. coli glutathionylspermidine synthetase/amidase and its predicted homologues YgiC and YjfC.  Int J Biochem Mol Biol. 2012; 3(3):302-312

Stourman NV, Branch MC, Schaab MR, Harp JM, Ladner JE, Armstrong RN. Structure and Function of YghU, a Nu-Class Glutathione Transferase Related to YfcG from Escherichia coli. Biochemistry, 2011 Jan 24. [Feb 22;50(7):1274-81.]

Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN. Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase.  Biochemistry. 2009 Jul 21;48(28):6559-61.