Lecture may be relatively easy to manage, as long as any visual aids (e.g., PowerPoint slides, whiteboard notes, working through problems) are easily seen by both audiences. Be sure to record class sessions in order to accommodate any student who may experience internet connectivity issues (Recording Using WebEx).
Be sure to keep an eye on your online participants, in case they raise a virtual hand, or put a question in the chat. It is good practice to set expectations about how students should ask questions during a lecture. Some instructors ask a student to keep an eye on the chat and inform them if there is a question or comment.