Dr. Nina Stourman

Professor
Dr. Nina Stourman - profile photo

Dr. Nina Stourman

Professor

Chemical & Biological Sciences

Ward Beecher Hall 6027

phone: (330) 941-7112

nvstourman@ysu.edu

Research Interests

Bacterial functional genomics, applications of enzymes

Teaching Interests

Biochemistry, Allied Health Chemistry, Chemical Toxicology

  • Education
    • 1992

      Ph D, Bioorganic Chemistry and Chemistry of Natural Bioactive Compounds

      Moscow State University (Russia)

    • 1984

      BS, Chemistry

      Moscow State University (Russia)

  • Awards and Honors
    • 2019

      YSU

      Distinguished Professor in Teaching Award

    • 2009

      Youngstown State University

      Research Professorship

  • Professional Positions
    • 2024 -

      Youngstown State University

      Professor

    • 2014 - 2024

      Youngstown State University

      Associate Professor

    • 2007 - 2014

      Youngstown State University

      Assistant Professor

    • 2004 - 2007

      Vanderbilt University

      Research Fellow

    • 2003 - 2004

      Roswell Park Cancer Institute

      Affiliate Member

    • 1999 - 2003

      Vanderbilt University

      Research Fellow

    • 1996 - 1999

      University of Tennessee

      Research Trainee

    • 1992 - 1993

      Hoffmann – La Roche, Inc

      Research Associate

  • Intellectual Contributions
    • 2023

      "Periplasmic β-glucosidase BglX from E. coli demonstrates greater activity towards galactose-containing substrates"

      N. Stourman, L. Ngo, J. Weimer, L. Sui, T. Pickens

      International Journal of Biochemistry and Molecular Biology, volume 14, issue 4, p. 76-86

    • 2018

      "Analysis of lactase in lactose intolerance supplements."

      N. Stourman, J. Moore

      Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, volume 46, issue 6, p. 652-662

    • 2013

      "Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure"

      N. Stourman, A. Ballester, L. Sui, Z. Morse

      SciKnow Publications; Biochemistry and Molecular Biology, volume 1, issue 3, p. 52

    • 2012

      "Comparison of the functions of glutathionylspermidine synthetase/amidase from E. coli and its predicted homologues YgiC and YjfC."

      L. Sui, J. Warren, J. Russell, N. Stourman

      International journal of biochemistry and molecular biology, volume 3, issue 3, p. 302-12

    • 2011

      "Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia coli."

      N. Stourman, M. Branch, M. Schaab, J. Harp, J. Ladner, R. Armstrong

      Biochemistry, volume 50, issue 7, p. 1274-81

    • 2009

      "Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase."

      M. Wadington, J. Ladner, N. Stourman, J. Harp, R. Armstrong

      Biochemistry, volume 48, issue 28, p. 6559-61

    • 2007

      "Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET."

      G. Lepesheva, M. Seliskar, C. Knutson, N. Stourman, D. Rozman, M. Waterman

      Archives of biochemistry and biophysics, volume 464, issue 2, p. 221-7

    • 2005

      "Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta."

      A. Varga, N. Stourman, Q. Zheng, A. Safina, L. Quan, X. Li , K. Sossey-Alaoui, A. Bakin

      Oncogene, volume 24, issue 32, p. 5043-52

    • 2005

      "Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins."

      A. Bakin, N. Stourman, K. Sekhar, C. Rinehart, X. Yan, M. Meredith, C. Arteaga, M. Freeman

      Free radical biology & medicine, volume 38, issue 3, p. 375-87

    • 2003

      "Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11."

      N. Stourman, J. Rose, S. Vuilleumier, R. Armstrong

      Biochemistry, volume 42, issue 37, p. 11048-56

    • 2002

      "Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase."

      S. Codreanu, J. Ladner, G. Xiao, N. Stourman, D. Hachey, G. Gilliland, R. Armstrong

      Biochemistry, volume 41, issue 51, p. 15161-72

    • 2001

      "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes."

      J. Wheeler, N. Stourman, R. Armstrong, F. Guengerich

      Chemical research in toxicology, volume 14, issue 8, p. 1107-17

    • 2001

      "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and dihalomethanes."

      J. Wheeler, N. Stourman, R. Thier, A. Dommermuth, S. Vuilleumier, J. Rose, R. Armstrong, F. Guengerich

      Chemical research in toxicology, volume 14, issue 8, p. 1118-27

    • "Crystal Structure Analysis of yghU from E. Coli"

      J. Harp, J. Ladner, M. Schaab, N. Stourman, R. Armstrong

      Worldwide Protein Data Bank

  • Professional Service
    • 2023 - 2024

      Other
      American Chemical Society

    • 2022 - present

      Reviewer, Journal Article
      Biochemistry (ACS)

  • Public Service
    • 2024 - 2024

      Organizer
      Jefferson High School Visit

    • 2024 - 2024

      Organizer
      Hands on Activities for STEAM class at Harding Elementary School

    • 2015 - 2015

      Volunteer
      North Road School visit

headshot


Education

B.S./M.S.: Moscow State University

Ph.D.: Moscow State University

Research Fellow: Vanderbilt University, Biochemistry, Nashville, TN, 1999-2003 & 2004-2007


Research Interests

Bacterial functional genomics during response to stress; bacterial glutathione metabolism


Publications

Nina Stourman, Jennifer Moore. Analysis of lactase in lactose intolerance supplements. Biochemistry and Molecular Biology Education, 46(6):652–662, 2018

Morse Z, Ballester A, Sui L, Stourman NV. Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure. Biochemistry & Molecular Biology (SciKnow Publications) (2013); 1(3): 52-57.

L Sui, JC Warren, JPN Russell, NV Stourman. Comparison of the functions of E. coli glutathionylspermidine synthetase/amidase and its predicted homologues YgiC and YjfC.  Int J Biochem Mol Biol. 2012; 3(3):302-312

Stourman NV, Branch MC, Schaab MR, Harp JM, Ladner JE, Armstrong RN. Structure and Function of YghU, a Nu-Class Glutathione Transferase Related to YfcG from Escherichia coli. Biochemistry, 2011 Jan 24. [Feb 22;50(7):1274-81.]

Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN. Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase.  Biochemistry. 2009 Jul 21;48(28):6559-61.