Nina Stourman

Dr. Nina Stourman - profile photo

Dr. Nina Stourman

Professor

Chemical & Biological Sciences

Ward Beecher Hall 6027

phone: (330) 941-7112

nvstourman@ysu.edu

Research Interests

Bacterial functional genomics, applications of enzymes

Teaching Interests

Biochemistry, Allied Health Chemistry, Chemical Toxicology

  • 1992

    Ph D, Bioorganic Chemistry and Chemistry of Natural Bioactive Compounds

    Moscow State University (Russia)

  • 1984

    BS, Chemistry

    Moscow State University (Russia)

  • 2019

    YSU

    Distinguished Professor in Teaching Award

  • 2009

    Youngstown State University

    Research Professorship

  • 2024 -

    Youngstown State University

    Professor

  • 2014 - 2024

    Youngstown State University

    Associate Professor

  • 2007 - 2014

    Youngstown State University

    Assistant Professor

  • 2004 - 2007

    Vanderbilt University

    Research Fellow

  • 2003 - 2004

    Roswell Park Cancer Institute

    Affiliate Member

  • 1999 - 2003

    Vanderbilt University

    Research Fellow

  • 1996 - 1999

    University of Tennessee

    Research Trainee

  • 1992 - 1993

    Hoffmann – La Roche, Inc

    Research Associate

  • 2023

    "Periplasmic β-glucosidase BglX from E. coli demonstrates greater activity towards galactose-containing substrates"

    N. Stourman, L. Ngo, J. Weimer, L. Sui, T. Pickens

    International Journal of Biochemistry and Molecular Biology, volume 14, issue 4, p. 76-86

  • 2018

    "Analysis of lactase in lactose intolerance supplements."

    N. Stourman, J. Moore

    Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, volume 46, issue 6, p. 652-662

  • 2013

    "Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure"

    N. Stourman, A. Ballester, L. Sui, Z. Morse

    SciKnow Publications; Biochemistry and Molecular Biology, volume 1, issue 3, p. 52

  • 2012

    "Comparison of the functions of glutathionylspermidine synthetase/amidase from E. coli and its predicted homologues YgiC and YjfC."

    L. Sui, J. Warren, J. Mitchell, N. Stourman

    International journal of biochemistry and molecular biology, volume 3, issue 3, p. 302-12

  • 2011

    "Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia coli."

    N. Stourman, M. Branch, M. Schaab, J. Harp, J. Ladner, R. Armstrong

    Biochemistry, volume 50, issue 7, p. 1274-81

  • 2009

    "Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase."

    M. Wadington, J. Ladner, N. Stourman, J. Harp, R. Armstrong

    Biochemistry, volume 48, issue 28, p. 6559-61

  • 2007

    "Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET."

    G. Lepesheva, M. Seliskar, C. Knutson, N. Stourman, D. Rozman, M. Waterman

    Archives of biochemistry and biophysics, volume 464, issue 2, p. 221-7

  • 2005

    "Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta."

    A. Varga, N. Stourman, Q. Zheng, A. Safina, L. Quan, X. Li , K. Sossey-Alaoui, A. Bakin

    Oncogene, volume 24, issue 32, p. 5043-52

  • 2005

    "Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins."

    A. Bakin, N. Stourman, K. Sekhar, C. Rinehart, X. Yan, M. Meredith, C. Arteaga, M. Freeman

    Free radical biology & medicine, volume 38, issue 3, p. 375-87

  • 2003

    "Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11."

    N. Stourman, J. Rose, S. Vuilleumier, R. Armstrong

    Biochemistry, volume 42, issue 37, p. 11048-56

  • 2002

    "Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase."

    S. Codreanu, J. Ladner, G. Xiao, N. Stourman, D. Hachey, G. Gilliland, R. Armstrong

    Biochemistry, volume 41, issue 51, p. 15161-72

  • 2001

    "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes."

    J. Wheeler, N. Stourman, R. Armstrong, F. Guengerich

    Chemical research in toxicology, volume 14, issue 8, p. 1107-17

  • 2001

    "Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and dihalomethanes."

    J. Wheeler, N. Stourman, R. Thier, A. Dommermuth, S. Vuilleumier, J. Rose, R. Armstrong, F. Guengerich

    Chemical research in toxicology, volume 14, issue 8, p. 1118-27

  • "Crystal Structure Analysis of yghU from E. Coli"

    J. Harp, J. Ladner, M. Schaab, N. Stourman, R. Armstrong

    Worldwide Protein Data Bank

  • 2023 - 2024

    Other
    American Chemical Society

  • 2022 - present

    Reviewer, Journal Article
    Biochemistry (ACS)

  • 2024 - 2024

    Organizer
    Jefferson High School Visit

  • 2024 - 2024

    Organizer
    Hands on Activities for STEAM class at Harding Elementary School

  • 2015 - 2015

    Volunteer
    North Road School visit

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Education

B.S./M.S.: Moscow State University

Ph.D.: Moscow State University

Research Fellow: Vanderbilt University, Biochemistry, Nashville, TN, 1999-2003 & 2004-2007

Research Interests

Bacterial functional genomics during response to stress; bacterial glutathione metabolism

Publications

Nina Stourman, Jennifer Moore. Analysis of lactase in lactose intolerance supplements. Biochemistry and Molecular Biology Education, 46(6):652–662, 2018

Morse Z, Ballester A, Sui L, Stourman NV. Glutathionylspermidine Conjugate as a Potential Protective Agent of DNA Damage Caused by Oxidative Stress and UV Exposure. Biochemistry & Molecular Biology (SciKnow Publications) (2013); 1(3): 52-57.

L Sui, JC Warren, JPN Russell, NV Stourman. Comparison of the functions of E. coli glutathionylspermidine synthetase/amidase and its predicted homologues YgiC and YjfC. Int J Biochem Mol Biol. 2012; 3(3):302-312

Stourman NV, Branch MC, Schaab MR, Harp JM, Ladner JE, Armstrong RN. Structure and Function of YghU, a Nu-Class Glutathione Transferase Related to YfcG from Escherichia coli. Biochemistry, 2011 Jan 24. [Feb 22;50(7):1274-81.]

Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN. Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase. Biochemistry. 2009 Jul 21;48(28):6559-61.